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Serum α-1 Antitrypsin (AAT) antagonizes intrinsic apoptosis induction in neutrophils from patients with systemic inflammatory response syndrome
Excessive neutrophil activation accompanied by delayed apoptotic cell death in inflammatory conditions causes progressive damage of cells and tissues, leading to life-threatening multiple organ dysfunction syndrome. Previous work suggested that circulating serum factors during inflammation are criti...
Autores principales: | Sarabhai, Theresia, Peter, Christoph, Bär, Anne-Kathrin, Windolf, Joachim, Relja, Borna, Wesselborg, Sebastian, Wahlers, Thorsten, Paunel-Görgülü, Adnana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426753/ https://www.ncbi.nlm.nih.gov/pubmed/28493974 http://dx.doi.org/10.1371/journal.pone.0177450 |
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