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Serum α-1 Antitrypsin (AAT) antagonizes intrinsic apoptosis induction in neutrophils from patients with systemic inflammatory response syndrome

Excessive neutrophil activation accompanied by delayed apoptotic cell death in inflammatory conditions causes progressive damage of cells and tissues, leading to life-threatening multiple organ dysfunction syndrome. Previous work suggested that circulating serum factors during inflammation are criti...

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Detalles Bibliográficos
Autores principales: Sarabhai, Theresia, Peter, Christoph, Bär, Anne-Kathrin, Windolf, Joachim, Relja, Borna, Wesselborg, Sebastian, Wahlers, Thorsten, Paunel-Görgülü, Adnana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426753/
https://www.ncbi.nlm.nih.gov/pubmed/28493974
http://dx.doi.org/10.1371/journal.pone.0177450