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Safety and tolerability of high-dose ulinastatin after 2-hour intravenous infusion in adult healthy Chinese volunteers: A randomized, double-blind, placebo-controlled, ascending-dose study

Ulinastatin, is a broad-spectrum protease inhibitor purified from human urine, inhibits endogenous proteases such as trypsin, α-chymotrypsin, hyaluronidase, and plasmin. It is widely being used at increasingly higher doses for the treatment of acute or chronic pancreatitis, severe infection, and acu...

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Detalles Bibliográficos
Autores principales: Chen, Qian, Hu, Chaoying, Liu, Ye, Liu, Yun, Wang, Wei, Zheng, Hongchao, Rong, Lianchen, Jia, Jingying, Sun, Shixuan, Yu, Chen, Liu, Yan Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426756/
https://www.ncbi.nlm.nih.gov/pubmed/28493932
http://dx.doi.org/10.1371/journal.pone.0177425