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Direct estrogen receptor (ER) / HER family crosstalk mediating sensitivity to lumretuzumab and pertuzumab in ER+ breast cancer

Bidirectional cross talk between members of the human epidermal growth factor family of receptors (HER) and the estrogen receptor (ER) is believed to underlie resistance mechanisms that develop in response to treatment with anti-HER agents and endocrine therapy. We investigated the interaction betwe...

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Detalles Bibliográficos
Autores principales: Collins, Denis, Jacob, Wolfgang, Cejalvo, Juan Miguel, Ceppi, Maurizio, James, Ian, Hasmann, Max, Crown, John, Cervantes, Andrés, Weisser, Martin, Bossenmaier, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426757/
https://www.ncbi.nlm.nih.gov/pubmed/28493933
http://dx.doi.org/10.1371/journal.pone.0177331