No evidence of genome editing activity from Natronobacterium gregoryi Argonaute (NgAgo) in human cells

The argonaute protein from the thermophilic bacterium Thermus thermophilus shows DNA-guided DNA interfering activity at high temperatures, complicating its application in mammalian cells. A recent work reported that the argonaute protein from Natronobacterium gregoryi (NgAgo) had DNA-guided genome e...

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Detalles Bibliográficos
Autores principales: Javidi-Parsijani, Parisa, Niu, Guoguang, Davis, Meghan, Lu, Pin, Atala, Anthony, Lu, Baisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426773/
https://www.ncbi.nlm.nih.gov/pubmed/28494027
http://dx.doi.org/10.1371/journal.pone.0177444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426773/
https://www.ncbi.nlm.nih.gov/pubmed/28494027
http://dx.doi.org/10.1371/journal.pone.0177444

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