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Identification of the SUMO E3 ligase PIAS1 as a potential survival biomarker in breast cancer

Metastasis is the ultimate cause of breast cancer related mortality. Epithelial-mesenchymal transition (EMT) is thought to play a crucial role in the metastatic potential of breast cancer. Growing evidence has implicated the SUMO E3 ligase PIAS1 in the regulation of EMT in mammary epithelial cells a...

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Detalles Bibliográficos
Autores principales: Chanda, Ayan, Chan, Angela, Deng, Lili, Kornaga, Elizabeth N., Enwere, Emeka K., Morris, Donald G., Bonni, Shirin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426774/
https://www.ncbi.nlm.nih.gov/pubmed/28493978
http://dx.doi.org/10.1371/journal.pone.0177639