Expression in Sf9 insect cells, purification and functional reconstitution of the human proton-coupled folate transporter (PCFT, SLC46A1)

The proton-coupled folate transporter (PCFT) provides an essential uptake route for the vitamin folic acid (B9) in mammals. In addition, it is currently of high interest for targeting chemotherapeutic agents to tumors due to the increased folic acid requirement of rapidly dividing tumor cells as wel...

Descripción completa

Detalles Bibliográficos
Autores principales: Date, Swapneeta S., Fiori, Mariana C., Altenberg, Guillermo A., Jansen, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426777/
https://www.ncbi.nlm.nih.gov/pubmed/28493963
http://dx.doi.org/10.1371/journal.pone.0177572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426777/
https://www.ncbi.nlm.nih.gov/pubmed/28493963
http://dx.doi.org/10.1371/journal.pone.0177572

Ejemplares similares