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Controlling transferrin receptor trafficking with GPI-valence in bloodstream stage African trypanosomes

Bloodstream-form African trypanosomes encode two structurally related glycosylphosphatidylinositol (GPI)-anchored proteins that are critical virulence factors, variant surface glycoprotein (VSG) for antigenic variation and transferrin receptor (TfR) for iron acquisition. Both are transcribed from th...

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Detalles Bibliográficos
Autores principales: Tiengwe, Calvin, Bush, Peter J., Bangs, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426795/
https://www.ncbi.nlm.nih.gov/pubmed/28459879
http://dx.doi.org/10.1371/journal.ppat.1006366