Cargando…

Controlling transferrin receptor trafficking with GPI-valence in bloodstream stage African trypanosomes

Bloodstream-form African trypanosomes encode two structurally related glycosylphosphatidylinositol (GPI)-anchored proteins that are critical virulence factors, variant surface glycoprotein (VSG) for antigenic variation and transferrin receptor (TfR) for iron acquisition. Both are transcribed from th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tiengwe, Calvin, Bush, Peter J., Bangs, James D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426795/ https://www.ncbi.nlm.nih.gov/pubmed/28459879 http://dx.doi.org/10.1371/journal.ppat.1006366

Ejemplares similares

Endoplasmic reticulum–associated degradation and disposal of misfolded GPI-anchored proteins in Trypanosoma brucei
por: Tiengwe, Calvin, et al.
Publicado: (2018)

A transferrin receptor’s guide to African trypanosomes
por: Urbaniak, Michael D., et al.
Publicado: (2023)

Stage-Specific COPII-Mediated Cargo Selectivity in African Trypanosomes
por: Sharif, Mohamed, et al.
Publicado: (2022)

Pseudokinase NRP1 facilitates endocytosis of transferrin in the African trypanosome
por: Kumar, Gaurav, et al.
Publicado: (2022)

Determinants of GPI-PLC Localisation to the Flagellum and Access to GPI-Anchored Substrates in Trypanosomes
por: Sunter, Jack, et al.
Publicado: (2013)

Bromodomain Proteins Contribute to Maintenance of Bloodstream Form Stage Identity in the African Trypanosome
por: Schulz, Danae, et al.
Publicado: (2015)

The Trypanosomal Transferrin Receptor of Trypanosoma Brucei—A Review
por: Kariuki, Christopher K., et al.
Publicado: (2019)

Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion
por: Trevor, Camilla E., et al.
Publicado: (2019)

Diversity in new flagellum tip attachment in bloodstream form African trypanosomes
por: Smithson, Laura, et al.
Publicado: (2022)

Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity
por: Liu, Ke, et al.
Publicado: (2016)

Controversy fuels trafficking of GPI-anchored proteins
por: Schuck, Sebastian, et al.
Publicado: (2006)

Unconventional endocytosis and trafficking of transferrin receptor induced by iron
por: Gammella, Elena, et al.
Publicado: (2021)

N-Linked Glycosylation Is Required for Transferrin-Induced Stabilization of Transferrin Receptor 2, but Not for Transferrin Binding or Trafficking to the Cell Surface
por: Zhao, Ningning, et al.
Publicado: (2013)

How Does the VSG Coat of Bloodstream Form African Trypanosomes Interact with External Proteins?
por: Schwede, Angela, et al.
Publicado: (2015)

Non-linear hierarchy of the quorum sensing signalling pathway in bloodstream form African trypanosomes
por: McDonald, Lindsay, et al.
Publicado: (2018)

Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome
por: Chandra, Monica, et al.
Publicado: (2023)

African trypanosomes
por: Cayla, Mathieu, et al.
Publicado: (2019)

Antibody affinity and valency impact brain uptake of transferrin receptor-targeted gold nanoparticles
por: Johnsen, Kasper Bendix, et al.
Publicado: (2018)

Trypanin, a Component of the Flagellar Dynein Regulatory Complex, Is Essential in Bloodstream Form African Trypanosomes
por: Ralston, Katherine S, et al.
Publicado: (2006)

Cytosolic Peroxidases Protect the Lysosome of Bloodstream African Trypanosomes from Iron-Mediated Membrane Damage
por: Hiller, Corinna, et al.
Publicado: (2014)

Apicobasal transferrin receptor localization and trafficking in brain capillary endothelial cells
por: Nielsen, Simone S. E., et al.
Publicado: (2023)

Exploiting the Achilles’ heel of membrane trafficking in trypanosomes
por: Zoltner, Martin, et al.
Publicado: (2016)

Imaging African trypanosomes
por: MacLean, L, et al.
Publicado: (2013)

Metabolic insights into phosphofructokinase inhibition in bloodstream-form trypanosomes
por: Nare, Zandile, et al.
Publicado: (2023)

Novel aspects of iron homeostasis in pathogenic bloodstream form Trypanosoma brucei
por: Gilabert Carbajo, Carla, et al.
Publicado: (2021)

Haptoglobin-hemoglobin receptor independent killing of African trypanosomes by human serum and trypanosome lytic factors
por: Bullard, Whitney, et al.
Publicado: (2012)

The molecular size of the extra-membrane domain influences the diffusion of the GPI-anchored VSG on the trypanosome plasma membrane
por: Hartel, Andreas J. W., et al.
Publicado: (2015)

Correction to: Apicobasal transferrin receptor localization and trafficking in brain capillary endothelial cells
por: Nielsen, Simone S. E., et al.
Publicado: (2023)

Social Motility in African Trypanosomes
por: Oberholzer, Michael, et al.
Publicado: (2010)

Antigenic variation in African trypanosomes
por: Horn, David
Publicado: (2014)

Trypanosome Motion Represents an Adaptation to the Crowded Environment of the Vertebrate Bloodstream
por: Heddergott, Niko, et al.
Publicado: (2012)

Genomic Occupancy of the Bromodomain Protein Bdf3 Is Dynamic during Differentiation of African Trypanosomes from Bloodstream to Procyclic Forms
por: Ashby, Ethan, et al.
Publicado: (2022)

mSphere of Influence: Modifying an Old Method To Study RNA-Protein Interactions
por: Tiengwe, Calvin
Publicado: (2019)

Early Invasion of Brain Parenchyma by African Trypanosomes
por: Frevert, Ute, et al.
Publicado: (2012)

The mitochondrial peroxiredoxin displays distinct roles in different developmental stages of African trypanosomes
por: Bogacz, Marta, et al.
Publicado: (2020)

The Killing of African Trypanosomes by Ethidium Bromide
por: Roy Chowdhury, Arnab, et al.
Publicado: (2010)

Cell–cell communication in African trypanosomes
por: McWilliam, K. R.
Publicado: (2023)

Ligand Valency Affects Transcytosis, Recycling and Intracellular Trafficking Mediated by the Neonatal Fc Receptor
por: Tesar, Devin B, et al.
Publicado: (2006)

Regulation of endocytic trafficking of transferrin receptor by optineurin and its impairment by a glaucoma-associated mutant
por: Nagabhushana, Ananthamurthy, et al.
Publicado: (2010)

PredGPI: a GPI-anchor predictor
por: Pierleoni, Andrea, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_rdb5cf17l8ml9nuv5u8q7p0bu5