Clustering of integrin α5 at the lateral membrane restores epithelial polarity in invasive colorectal cancer cells

Apicobasolateral polarity is a fundamental property of epithelial cells, and its loss is a hallmark of cancer. Integrin-mediated contact with the extracellular matrix defines the basal surface, setting in motion E-cadherin–mediated cell–cell contact, which establishes apicobasolateral polarity. Role...

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Detalles Bibliográficos
Autores principales: Starchenko, Alina, Graves-Deal, Ramona, Yang, Yu-Ping, Li, Cunxi, Zent, Roy, Singh, Bhuminder, Coffey, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426844/
https://www.ncbi.nlm.nih.gov/pubmed/28356422
http://dx.doi.org/10.1091/mbc.E16-12-0852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426844/
https://www.ncbi.nlm.nih.gov/pubmed/28356422
http://dx.doi.org/10.1091/mbc.E16-12-0852

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