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Efficiency of lamellipodia protrusion is determined by the extent of cytosolic actin assembly

Cell migration and cell–cell communication involve the protrusion of actin-rich cell surface projections such as lamellipodia and filopodia. Lamellipodia are networks of actin filaments generated and turned over by filament branching through the Arp2/3 complex. Inhibition of branching is commonly ag...

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Detalles Bibliográficos
Autores principales: Dimchev, Georgi, Steffen, Anika, Kage, Frieda, Dimchev, Vanessa, Pernier, Julien, Carlier, Marie-France, Rottner, Klemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426846/
https://www.ncbi.nlm.nih.gov/pubmed/28331069
http://dx.doi.org/10.1091/mbc.E16-05-0334