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Memory CD4 T cell subsets are kinetically heterogeneous and replenished from naive T cells at high levels

Characterising the longevity of immunological memory requires establishing the rules underlying the renewal and death of peripheral T cells. However, we lack knowledge of the population structure and how self-renewal and de novo influx contribute to the maintenance of memory compartments. Here, we c...

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Detalles Bibliográficos
Autores principales: Gossel, Graeme, Hogan, Thea, Cownden, Daniel, Seddon, Benedict, Yates, Andrew J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426903/
https://www.ncbi.nlm.nih.gov/pubmed/28282024
http://dx.doi.org/10.7554/eLife.23013