Generation of mature T cells from human hematopoietic stem/progenitor cells in artificial thymic organoids

Studies of human T cell development require robust model systems that recapitulate the full span of thymopoiesis, from hematopoietic stem and progenitor cells (HSPCs) through to mature T cells. Existing in vitro models induce T cell commitment from human HSPCs; however, differentiation into mature C...

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Detalles Bibliográficos
Autores principales: Seet, Christopher S., He, Chongbin, Bethune, Michael T., Li, Suwen, Chick, Brent, Gschweng, Eric H., Zhu, Yuhua, Kim, Kenneth, Kohn, Donald B., Baltimore, David, Crooks, Gay M., Montel-Hagen, Amélie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426913/
https://www.ncbi.nlm.nih.gov/pubmed/28369043
http://dx.doi.org/10.1038/nmeth.4237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426913/
https://www.ncbi.nlm.nih.gov/pubmed/28369043
http://dx.doi.org/10.1038/nmeth.4237

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