The Pharmacogenetics of Tacrolimus in Corticosteroid-Sparse Pediatric and Adult Kidney Transplant Recipients

INTRODUCTION: Tacrolimus is a calcineurin inhibitor used as an immunosuppressant drug in solid organ transplantation, and is mainly metabolized by cytochrome P450 (CYP) 3A4 and CYP3A5. Studies have shown an association between the CYP3A5 genotype and tacrolimus dose-adjusted trough concentrations. V...

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Detalles Bibliográficos
Autores principales: Madsen, Mads Juul, Bergmann, Troels K., Brøsen, Kim, Thiesson, Helle Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427048/
https://www.ncbi.nlm.nih.gov/pubmed/28229376
http://dx.doi.org/10.1007/s40268-017-0177-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427048/
https://www.ncbi.nlm.nih.gov/pubmed/28229376
http://dx.doi.org/10.1007/s40268-017-0177-9

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