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Solubilization and Stability of Mitomycin C Solutions Prepared for Intravesical Administration

BACKGROUND: Mitomycin C (MMC) is an antitumor agent that is often administered intravesically to treat bladder cancer. Pharmacologically optimized studies have suggested varying methods to optimize delivery, with drug concentration and solution volume being the main drivers. However, these MMC conce...

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Detalles Bibliográficos
Autores principales: Myers, Alan L., Zhang, Yan-Ping, Kawedia, Jitesh D., Zhou, Ximin, Sobocinski, Stacey M., Metcalfe, Michael J., Kramer, Mark A., Dinney, Colin P. N., Kamat, Ashish M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427054/
https://www.ncbi.nlm.nih.gov/pubmed/28470465
http://dx.doi.org/10.1007/s40268-017-0183-y