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Chronic Monoarthritis Pain Accelerates the Processes of Cognitive Impairment and Increases the NMDAR Subunits NR2B in CA3 of Hippocampus from 5-month-old Transgenic APP/PS1 Mice

Many factors impact cognitive impairment; however, the effects of chronic pain and the mechanisms underlying these effects on cognitive impairment are currently unknown. Here we tested the hypothesis that chronic pain accelerates the transition from normal cognition to mild cognitive impairment (MCI...

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Detalles Bibliográficos
Autores principales: Gong, Wei-Yi, Wang, Rong, Liu, Yuan, Jin, He, Zhao, Zhi-Wei, Wang, Yu-Lan, Li, Hong-Yan, Zhang, Xu, Ni, Jia-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427068/
https://www.ncbi.nlm.nih.gov/pubmed/28553223
http://dx.doi.org/10.3389/fnagi.2017.00123