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ASCT2 (SLC1A5)-Deficient Mice Have Normal B-Cell Development, Proliferation, and Antibody Production

SLC1A5 (solute carrier family 1, member 5) is a small neutral amino acid exchanger that is upregulated in rapidly proliferating lymphocytes but also in many primary human cancers. Furthermore, cancer cell lines have been shown to require SLC1A5 for their survival in vitro. One of SLC1A5’s primary su...

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Detalles Bibliográficos
Autores principales: Masle-Farquhar, Etienne, Bröer, Angelika, Yabas, Mehmet, Enders, Anselm, Bröer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427077/
https://www.ncbi.nlm.nih.gov/pubmed/28553292
http://dx.doi.org/10.3389/fimmu.2017.00549