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Meta Analysis of Human AlzGene Database: Benefits and Limitations of Using C. elegans for the Study of Alzheimer's Disease and Co-morbid Conditions

Human genome-wide association studies (GWAS) and linkage studies have identified 695 genes associated with Alzheimer's disease (AD), the vast majority of which are associated with late-onset AD. Although orthologs of these AD genes have been studied in several model species, orthologs in the ne...

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Detalles Bibliográficos
Autores principales: Vahdati Nia, Behrad, Kang, Christine, Tran, Michelle G., Lee, Deborah, Murakami, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427079/
https://www.ncbi.nlm.nih.gov/pubmed/28553317
http://dx.doi.org/10.3389/fgene.2017.00055