Selective Transgenic Expression of Mutant Ubiquitin in Purkinje Cell Stripes in the Cerebellum

The ubiquitin-proteasome system (UPS) is one of the major mechanisms for protein breakdown in cells, targeting proteins for degradation by enzymatically conjugating them to ubiquitin molecules. Intracellular accumulation of ubiquitin-B(+1) (UBB(+1)), a frameshift mutant of ubiquitin-B, is indicative...

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Detalles Bibliográficos
Autores principales: Verheijen, Bert M., Gentier, Romina J. G., Hermes, Denise J. H. P., van Leeuwen, Fred W., Hopkins, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427096/
https://www.ncbi.nlm.nih.gov/pubmed/27966098
http://dx.doi.org/10.1007/s12311-016-0838-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427096/
https://www.ncbi.nlm.nih.gov/pubmed/27966098
http://dx.doi.org/10.1007/s12311-016-0838-1

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