A83-01 inhibits TGF-β-induced upregulation of Wnt3 and epithelial to mesenchymal transition in HER2-overexpressing breast cancer cells

PURPOSE: The aim of this study is to investigate the mechanisms of interactions between TGF-β and Wnt/β-catenin pathways that induce and regulate EMT and promote breast cancer cells to become resistant to treatment. METHODS: The effect of TGF-β on Wnt/β-catenin signaling pathway was examined by usin...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Yanyuan, Tran, Trinh, Dwabe, Sami, Sarkissyan, Marianna, Kim, Juri, Nava, Miguel, Clayton, Sheilah, Pietras, Richard, Farias-Eisner, Robin, Vadgama, Jaydutt V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Preclinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427117/
https://www.ncbi.nlm.nih.gov/pubmed/28337662
http://dx.doi.org/10.1007/s10549-017-4211-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427117/
https://www.ncbi.nlm.nih.gov/pubmed/28337662
http://dx.doi.org/10.1007/s10549-017-4211-y

Ejemplares similares