Effect of clopidogrel on the hydroxylation and sulfoxidation of omeprazole: A single dose study in healthy human volunteers

Based upon the known potential interaction between omeprazole (OMP) and clopidogrel (CLOP), the current study was designed to evaluate the effect of CLOP on disposition of OMP and its two major metabolites, 5-hydroxyomeprazole (5-OH-OMP) and omeprazole sulfone (OMP-S) in healthy clinical subjects. A...

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Detalles Bibliográficos
Autores principales: Ahmad, Lateef, Iqbal, Zafar, Nazir, Shabnam, Khan, Abad, Shah, Yasar, Khan, Muhammad Imran, Khan, Ismail, Khan, Amjad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427475/
https://www.ncbi.nlm.nih.gov/pubmed/28507476
http://dx.doi.org/10.17179/excli2016-658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427475/
https://www.ncbi.nlm.nih.gov/pubmed/28507476
http://dx.doi.org/10.17179/excli2016-658

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