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The Interaction of Genetic Background and Mutational Effects in Regulation of Mouse Craniofacial Shape
Inbred genetic background significantly influences the expression of phenotypes associated with known genetic perturbations and can underlie variation in disease severity between individuals with the same mutation. However, the effect of epistatic interactions on the development of complex traits, s...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Genetics Society of America
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427488/ https://www.ncbi.nlm.nih.gov/pubmed/28280213 http://dx.doi.org/10.1534/g3.117.040659 |