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asymptoticMK: A Web-Based Tool for the Asymptotic McDonald–Kreitman Test

The McDonald–Kreitman (MK) test is a widely used method for quantifying the role of positive selection in molecular evolution. One key shortcoming of this test lies in its sensitivity to the presence of slightly deleterious mutations, which can severely bias its estimates. An asymptotic version of t...

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Detalles Bibliográficos
Autores principales: Haller, Benjamin C., Messer, Philipp W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427504/
https://www.ncbi.nlm.nih.gov/pubmed/28341700
http://dx.doi.org/10.1534/g3.117.039693