Nuclear-targeted siRNA delivery for long-term gene silencing

Developing effective nonviral siRNA delivery systems for long-term gene silencing remains a great challenge. Here we present a nuclear-targeted siRNA delivery system that can induce long-term gene silencing in cancer cells. The nanocarrier consists of gold nanoparticles modified with a dense shell o...

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Detalles Bibliográficos
Autores principales: Li, Na, Yang, Huijun, Yu, Zhengze, Li, Yanli, Pan, Wei, Wang, Hongyu, Tang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427680/
https://www.ncbi.nlm.nih.gov/pubmed/28553519
http://dx.doi.org/10.1039/c6sc04293g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427680/
https://www.ncbi.nlm.nih.gov/pubmed/28553519
http://dx.doi.org/10.1039/c6sc04293g

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