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Nuclear-targeted siRNA delivery for long-term gene silencing

Developing effective nonviral siRNA delivery systems for long-term gene silencing remains a great challenge. Here we present a nuclear-targeted siRNA delivery system that can induce long-term gene silencing in cancer cells. The nanocarrier consists of gold nanoparticles modified with a dense shell o...

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Detalles Bibliográficos
Autores principales:	Li, Na, Yang, Huijun, Yu, Zhengze, Li, Yanli, Pan, Wei, Wang, Hongyu, Tang, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2017
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427680/ https://www.ncbi.nlm.nih.gov/pubmed/28553519 http://dx.doi.org/10.1039/c6sc04293g

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