Lack of XPC leads to a shift between respiratory complexes I and II but sensitizes cells to mitochondrial stress

Genomic instability drives tumorigenesis and DNA repair defects are associated with elevated cancer. Metabolic alterations are also observed during tumorigenesis, although a causal relationship between these has not been clearly established. Xeroderma pigmentosum (XP) is a DNA repair disease charact...

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Detalles Bibliográficos
Autores principales: Mori, Mateus P., Costa, Rute A. P., Soltys, Daniela T., Freire, Thiago de S., Rossato, Franco A., Amigo, Ignácio, Kowaltowski, Alicia J., Vercesi, Aníbal E., de Souza-Pinto, Nadja C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427820/
https://www.ncbi.nlm.nih.gov/pubmed/28273955
http://dx.doi.org/10.1038/s41598-017-00130-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427820/
https://www.ncbi.nlm.nih.gov/pubmed/28273955
http://dx.doi.org/10.1038/s41598-017-00130-x

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