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Lack of XPC leads to a shift between respiratory complexes I and II but sensitizes cells to mitochondrial stress
Genomic instability drives tumorigenesis and DNA repair defects are associated with elevated cancer. Metabolic alterations are also observed during tumorigenesis, although a causal relationship between these has not been clearly established. Xeroderma pigmentosum (XP) is a DNA repair disease charact...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427820/ https://www.ncbi.nlm.nih.gov/pubmed/28273955 http://dx.doi.org/10.1038/s41598-017-00130-x |