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Proteomic analysis of proteome and histone post-translational modifications in heat shock protein 90 inhibition-mediated bladder cancer therapeutics

Heat shock protein 90 (HSP90) inhibition is an attractive strategy for cancer treatment. Several HSP90 inhibitors have shown promising effects in clinical oncology trials. However, little is known about HSP90 inhibition-mediated bladder cancer therapy. Here, we report a quantitative proteomic study...

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Detalles Bibliográficos
Autores principales: Li, Qingdi Quentin, Hao, Jian-Jiang, Zhang, Zheng, Krane, L. Spencer, Hammerich, Kai H., Sanford, Thomas, Trepel, Jane B., Neckers, Len, Agarwal, Piyush K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427839/
https://www.ncbi.nlm.nih.gov/pubmed/28298630
http://dx.doi.org/10.1038/s41598-017-00143-6