CCR5 promoter activity correlates with HIV disease progression by regulating CCR5 cell surface expression and CD4 T cell apoptosis

CCR5 is the major co-receptor for HIV and polymorphisms in the CCR5 gene as well as promoter region that alter cell surface expression have been associated with disease progression. We determined the relationship between CCR5 promoter polymorphisms and CD4 decline and other immunopathological featur...

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Detalles Bibliográficos
Autores principales: Joshi, Anjali, Punke, Erin B., Sedano, Melina, Beauchamp, Bethany, Patel, Rima, Hossenlopp, Cassady, Alozie, Ogechika K., Gupta, Jayanta, Mukherjee, Debabrata, Garg, Himanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427887/
https://www.ncbi.nlm.nih.gov/pubmed/28331180
http://dx.doi.org/10.1038/s41598-017-00192-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427887/
https://www.ncbi.nlm.nih.gov/pubmed/28331180
http://dx.doi.org/10.1038/s41598-017-00192-x

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