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RNA-Sequencing data supports the existence of novel VEGFA splicing events but not of VEGFA(xxx)b isoforms
Vascular endothelial growth factor (VEGFA), a pivotal regulator of angiogenesis and valuable therapeutic target, is characterised by alternative splicing which generates three principal isoforms, VEGFA(121), VEGFA(165) and VEGFA(189). A second set of anti-angiogenic isoforms termed VEGFA(xxx)b that...
Autores principales: | Bridgett, Stephen, Dellett, Margaret, Simpson, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427905/ https://www.ncbi.nlm.nih.gov/pubmed/28246395 http://dx.doi.org/10.1038/s41598-017-00100-3 |
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