Rescue of the MERTK phagocytic defect in a human iPSC disease model using translational read-through inducing drugs

Inherited retinal dystrophies are an important cause of blindness, for which currently there are no effective treatments. In order to study this heterogeneous group of diseases, adequate disease models are required in order to better understand pathology and to test potential therapies. Induced plur...

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Detalles Bibliográficos
Autores principales: Ramsden, Conor M., Nommiste, Britta, R. Lane, Amelia, Carr, Amanda-Jayne F., Powner, Michael B., J. K. Smart, Matthew, Chen, Li Li, Muthiah, Manickam N., Webster, Andrew R., Moore, Anthony T., Cheetham, Michael E., da Cruz, Lyndon, Coffey, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427915/
https://www.ncbi.nlm.nih.gov/pubmed/28246391
http://dx.doi.org/10.1038/s41598-017-00142-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427915/
https://www.ncbi.nlm.nih.gov/pubmed/28246391
http://dx.doi.org/10.1038/s41598-017-00142-7

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