PRL3 phosphatase active site is required for binding the putative magnesium transporter CNNM3

The phosphatases of regenerating liver (PRLs) are involved in tumorigenesis and metastatic cancer yet their cellular function remains unclear. Recent reports have shown PRL phosphatases bind tightly to the CNNM family of membrane proteins to regulate magnesium efflux. Here, we characterize the inter...

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Detalles Bibliográficos
Autores principales: Zhang, Huizhi, Kozlov, Guennadi, Li, Xinlu, Wu, Howie, Gulerez, Irina, Gehring, Kalle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427921/
https://www.ncbi.nlm.nih.gov/pubmed/28246390
http://dx.doi.org/10.1038/s41598-017-00147-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427921/
https://www.ncbi.nlm.nih.gov/pubmed/28246390
http://dx.doi.org/10.1038/s41598-017-00147-2

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