Towards Celiac-safe foods: Decreasing the affinity of transglutaminase 2 for gliadin by addition of ascorbyl palmitate and ZnCl(2) as detoxifiers

Initiation of celiac disease is triggered in the gastrointestinal tract by transglutaminase 2 (TG2) assisted deamidation of gluten peptides. Deamidation is a side-reaction to transamidation and occurs if primary amines are absent. In contrast to deamidation, transamidation does not trigger an immune...

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Detalles Bibliográficos
Autores principales: Engstrom, N., Saenz-Méndez, P., Scheers, J., Scheers, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427931/
https://www.ncbi.nlm.nih.gov/pubmed/28250436
http://dx.doi.org/10.1038/s41598-017-00174-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427931/
https://www.ncbi.nlm.nih.gov/pubmed/28250436
http://dx.doi.org/10.1038/s41598-017-00174-z

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