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De novo [PSI(+)] prion formation involves multiple pathways to form infectious oligomers
Prion and other neurodegenerative diseases are associated with misfolded protein assemblies called amyloid. Research has begun to uncover common mechanisms underlying transmission of amyloids, yet how amyloids form in vivo is still unclear. Here, we take advantage of the yeast prion, [PSI (+)], to u...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427932/ https://www.ncbi.nlm.nih.gov/pubmed/28250435 http://dx.doi.org/10.1038/s41598-017-00135-6 |