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Robust Analysis of Fluxes in Genome-Scale Metabolic Pathways
Constraint-based optimization, such as flux balance analysis (FBA), has become a standard systems-biology computational method to study cellular metabolisms that are assumed to be in a steady state of optimal growth. The methods are based on optimization while assuming (i) equilibrium of a linear sy...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427939/ https://www.ncbi.nlm.nih.gov/pubmed/28325918 http://dx.doi.org/10.1038/s41598-017-00170-3 |