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Disentangling constraints using viability evolution principles in integrative modeling of macromolecular assemblies

Predicting the structure of large molecular assemblies remains a challenging task in structural biology when using integrative modeling approaches. One of the main issues stems from the treatment of heterogeneous experimental data used to predict the architecture of native complexes. We propose a ne...

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Detalles Bibliográficos
Autores principales: Tamò, Giorgio, Maesani, Andrea, Träger, Sylvain, Degiacomi, Matteo T., Floreano, Dario, Dal Peraro, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427971/
https://www.ncbi.nlm.nih.gov/pubmed/28331186
http://dx.doi.org/10.1038/s41598-017-00266-w