Cargando…
Bilirubin augments Ca(2+) load of developing bushy neurons by targeting specific subtype of voltage-gated calcium channels
Neonatal brain is particularly vulnerable to pathological levels of bilirubin which elevates and overloads intracellular Ca(2+), leading to neurotoxicity. However, how voltage-gated calcium channels (VGCCs) are functionally involved in excess calcium influx remains unknown. By performing voltage-cla...
Autores principales: | Liang, Min, Yin, Xin-Lu, Shi, Hai-Bo, Li, Chun-Yan, Li, Xin-Yi, Song, Ning-Ying, Shi, Hao-Song, Zhao, Yi, Wang, Lu-Yang, Yin, Shan-Kai |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427978/ https://www.ncbi.nlm.nih.gov/pubmed/28348377 http://dx.doi.org/10.1038/s41598-017-00275-9 |
Ejemplares similares
-
Ca(2+)-dependent recruitment of voltage-gated sodium channels underlies bilirubin-induced overexcitation and neurotoxicity
por: Shi, Hao-Song, et al.
Publicado: (2019) -
Bilirubin gates the TRPM2 channel as a direct agonist to exacerbate ischemic brain damage
por: Liu, Han-Wei, et al.
Publicado: (2023) -
Downregulation of L‐Type Voltage‐Gated Ca(2+), Voltage‐Gated K(+), and Large‐Conductance Ca(2+)‐Activated K(+) Channels in Vascular Myocytes From Salt‐Loading Offspring Rats Exposed to Prenatal Hypoxia
por: Liu, Bailin, et al.
Publicado: (2018) -
Optogenetic Control of Voltage‐Gated Calcium Channels
por: Ma, Guolin, et al.
Publicado: (2018) -
Molecular insights into the gating mechanisms of voltage-gated calcium channel Ca(V)2.3
por: Gao, Yiwei, et al.
Publicado: (2023)