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Genome-wide methylation analysis of a large population sample shows neurological pathways involvement in chronic widespread musculoskeletal pain

Chronic widespread musculoskeletal pain (CWP), has a considerable heritable component, which remains to be explained. Epigenetic factors may contribute to and account for some of the heritability estimate. We analysed epigenome-wide methylation using MeDIPseq in whole blood DNA from 1708 monozygotic...

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Detalles Bibliográficos
Autores principales: Livshits, Gregory, Malkin, Ida, Freidin, Maxim B., Xia, Yudong, Gao, Fei, Wang, Jun, Spector, Timothy D., MacGregor, Alex, Bell, Jordana T., Williams, Frances M.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427989/
https://www.ncbi.nlm.nih.gov/pubmed/28221285
http://dx.doi.org/10.1097/j.pain.0000000000000880