Targeting to the non-genomic activity of retinoic acid receptor-gamma by acacetin in hepatocellular carcinoma

We recently demonstrated that retinoic acid receptor-γ (RARγ) is overexpressed and acts as a tumor promoter in hepatocellular carcinoma (HCC). The oncogenic activity of RARγ is mainly attributed to its physiological interaction with p85α regulatory subunit of PI3K leading to constitutive activation...

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Detalles Bibliográficos
Autores principales: Zeng, Wenjun, Zhang, Chunyun, Cheng, Hongwei, Wu, Yun-Long, Liu, Jie, Chen, Zekun, Huang, Jian-gang, Ericksen, Russell Erick, Chen, Liqun, Zhang, Haiping, Wong, Alice Sze Tsai, Zhang, Xiao-kun, Han, Weiping, Zeng, Jin-Zhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428017/
https://www.ncbi.nlm.nih.gov/pubmed/28336971
http://dx.doi.org/10.1038/s41598-017-00233-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428017/
https://www.ncbi.nlm.nih.gov/pubmed/28336971
http://dx.doi.org/10.1038/s41598-017-00233-5

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