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Dysregulation of mCD46 and sCD46 contribute to the pathogenesis of bullous pemphigoid
Bullous pemphigoid (BP) is an autoimmune bullous disease caused by autoantibodies against BP180 in the epidermal basement membrane. Autoantibody-mediated complement activation is an important process in BP pathogenesis. CD46, a crucial complement regulatory protein in the complement activation, has...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428046/ https://www.ncbi.nlm.nih.gov/pubmed/28273946 http://dx.doi.org/10.1038/s41598-017-00235-3 |