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Dysregulation of mCD46 and sCD46 contribute to the pathogenesis of bullous pemphigoid

Bullous pemphigoid (BP) is an autoimmune bullous disease caused by autoantibodies against BP180 in the epidermal basement membrane. Autoantibody-mediated complement activation is an important process in BP pathogenesis. CD46, a crucial complement regulatory protein in the complement activation, has...

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Detalles Bibliográficos
Autores principales: Qiao, Pei, Dang, Erle, Cao, Tianyu, Fang, Hui, Zhang, Jieyu, Qiao, Hongjiang, Wang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428046/
https://www.ncbi.nlm.nih.gov/pubmed/28273946
http://dx.doi.org/10.1038/s41598-017-00235-3