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Experimental mitochondria-targeted DNA methylation identifies GpC methylation, not CpG methylation, as potential regulator of mitochondrial gene expression

Like the nucleus, mitochondria contain their own DNA and recent reports provide accumulating evidence that also the mitochondrial DNA (mtDNA) is subjective to DNA methylation. This evidence includes the demonstration of mitochondria-localised DNA methyltransferases and demethylases, and the detectio...

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Detalles Bibliográficos
Autores principales: van der Wijst, Monique G. P., van Tilburg, Amanda Y., Ruiters, Marcel H. J., Rots, Marianne G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428053/
https://www.ncbi.nlm.nih.gov/pubmed/28282966
http://dx.doi.org/10.1038/s41598-017-00263-z