NMR monitoring of the SELEX process to confirm enrichment of structured RNA

RNA aptamers are RNA molecules that bind to a target molecule with high affinity and specificity using uniquely-folded tertiary structures. RNA aptamers are selected from an RNA pool typically comprising up to 10(15) different sequences generated by iterative steps of selection and amplification kno...

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Detalles Bibliográficos
Autores principales: Amano, Ryo, Aoki, Kazuteru, Miyakawa, Shin, Nakamura, Yoshikazu, Kozu, Tomoko, Kawai, Gota, Sakamoto, Taiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428055/
https://www.ncbi.nlm.nih.gov/pubmed/28325909
http://dx.doi.org/10.1038/s41598-017-00273-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428055/
https://www.ncbi.nlm.nih.gov/pubmed/28325909
http://dx.doi.org/10.1038/s41598-017-00273-x

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