Elevated COX-2 Expression Promotes Angiogenesis Through EGFR/p38-MAPK/Sp1-Dependent Signalling in Pancreatic Cancer

Cyclooxygenase-2 (COX-2) was stated to be overexpression in various human malignancies associating with angiogenesis, metastasis and chemoresistence. Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease displaying many of these characteristics. A common abnormality of PDAC is overexpression o...

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Detalles Bibliográficos
Autores principales: Hu, Hai, Han, Ting, Zhuo, Meng, Wu, Lei-lei, Yuan, Cuncun, Wu, Lixia, Lei, Wang, Jiao, Feng, Wang, Li-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428057/
https://www.ncbi.nlm.nih.gov/pubmed/28352075
http://dx.doi.org/10.1038/s41598-017-00288-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428057/
https://www.ncbi.nlm.nih.gov/pubmed/28352075
http://dx.doi.org/10.1038/s41598-017-00288-4

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