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Length-dependent gene misexpression is associated with Alzheimer’s disease progression

Recent reports show transcription preference for long genes in neuronal tissues compared with non-neuronal tissues, and a gene-length dependent change in expression in the neurodevelopmental disease Rett syndrome (RTT). Whether the gene-length dependent changes in expression seen in RTT might also b...

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Detalles Bibliográficos
Autores principales: Barbash, Shahar, Sakmar, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428066/
https://www.ncbi.nlm.nih.gov/pubmed/28298623
http://dx.doi.org/10.1038/s41598-017-00250-4