PEGylated insulin-like growth factor-I affords protection and facilitates recovery of lost functions post-focal ischemia

Insulin-like growth factor-I (IGF-I) is involved in the maturation and maintenance of neurons, and impaired IGF-I signaling has been shown to play a role in various neurological diseases including stroke. The aim of the present study was to investigate the efficacy of an optimized IGF-I variant by a...

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Detalles Bibliográficos
Autores principales: Parker, Kim, Berretta, Antonio, Saenger, Stefanie, Sivaramakrishnan, Manaswini, Shirley, Simon A., Metzger, Friedrich, Clarkson, Andrew N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428211/
https://www.ncbi.nlm.nih.gov/pubmed/28325900
http://dx.doi.org/10.1038/s41598-017-00336-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428211/
https://www.ncbi.nlm.nih.gov/pubmed/28325900
http://dx.doi.org/10.1038/s41598-017-00336-z

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