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PEGylated insulin-like growth factor-I affords protection and facilitates recovery of lost functions post-focal ischemia
Insulin-like growth factor-I (IGF-I) is involved in the maturation and maintenance of neurons, and impaired IGF-I signaling has been shown to play a role in various neurological diseases including stroke. The aim of the present study was to investigate the efficacy of an optimized IGF-I variant by a...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428211/ https://www.ncbi.nlm.nih.gov/pubmed/28325900 http://dx.doi.org/10.1038/s41598-017-00336-z |