Egg antigen p40 of Schistosoma japonicum promotes senescence in activated hepatic stellate cells via SKP2/P27 signaling pathway

Schistosomiasis is characterized by egg deposition, granulomatous inflammatory reaction and then subsequent hepatic fibrosis formation. Activated HSCs are regarded as the main effector cells in the progression of liver fibrosis and induction of senescence in hepatic stellate cells (HSCs) is vital to...

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Detalles Bibliográficos
Autores principales: Xu, Tianhua, Chen, Jinling, Zhu, Dandan, Chen, Liuting, Wang, Jianxin, Sun, Xiaolei, Hu, Bin, Duan, Yinong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428252/
https://www.ncbi.nlm.nih.gov/pubmed/28325896
http://dx.doi.org/10.1038/s41598-017-00326-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428252/
https://www.ncbi.nlm.nih.gov/pubmed/28325896
http://dx.doi.org/10.1038/s41598-017-00326-1

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