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Lysosomal activity maintains glycolysis and cyclin E1 expression by mediating Ad4BP/SF-1 stability for proper steroidogenic cell growth

The development and differentiation of steroidogenic organs are controlled by Ad4BP/SF-1 (adrenal 4 binding protein/steroidogenic factor 1). Besides, lysosomal activity is required for steroidogenesis and also enables adrenocortical cell to survive during stress. However, the role of lysosomal activ...

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Detalles Bibliográficos
Autores principales: Syu, Jhih-Siang, Baba, Takashi, Huang, Jyun-Yuan, Ogawa, Hidesato, Hsieh, Chi-Han, Hu, Jin-Xian, Chen, Ting-Yu, Lin, Tzu-Chien, Tsuchiya, Megumi, Morohashi, Ken-Ichirou, Huang, Bu-Miin, Lu, Fu-l., Wang, Chia-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428257/
https://www.ncbi.nlm.nih.gov/pubmed/28325912
http://dx.doi.org/10.1038/s41598-017-00393-4