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Lysosomal activity maintains glycolysis and cyclin E1 expression by mediating Ad4BP/SF-1 stability for proper steroidogenic cell growth
The development and differentiation of steroidogenic organs are controlled by Ad4BP/SF-1 (adrenal 4 binding protein/steroidogenic factor 1). Besides, lysosomal activity is required for steroidogenesis and also enables adrenocortical cell to survive during stress. However, the role of lysosomal activ...
Autores principales: | Syu, Jhih-Siang, Baba, Takashi, Huang, Jyun-Yuan, Ogawa, Hidesato, Hsieh, Chi-Han, Hu, Jin-Xian, Chen, Ting-Yu, Lin, Tzu-Chien, Tsuchiya, Megumi, Morohashi, Ken-Ichirou, Huang, Bu-Miin, Lu, Fu-l., Wang, Chia-Yih |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428257/ https://www.ncbi.nlm.nih.gov/pubmed/28325912 http://dx.doi.org/10.1038/s41598-017-00393-4 |
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