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Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission

The amyloid precursor protein (APP) modulates synaptic activity, resulting from the fine tuning of excitatory and inhibitory neurotransmission. GABAergic inhibitory neurotransmission is affected by modifications in intracellular chloride concentrations regulated by Na(+)-K(+)-2Cl(−) cotransporter 1...

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Detalles Bibliográficos
Autores principales: Doshina, Anna, Gourgue, Florian, Onizuka, Michiho, Opsomer, Remi, Wang, Peng, Ando, Kunie, Tasiaux, Bernadette, Dewachter, Ilse, Kienlen-Campard, Pascal, Brion, Jean-Pierre, Gailly, Philippe, Octave, Jean-Noël, Pierrot, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428293/
https://www.ncbi.nlm.nih.gov/pubmed/28337033
http://dx.doi.org/10.1038/s41598-017-00325-2